ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeK527N

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: penicillin-binding protein PBP3 FtsI
Resistance To: cephalosporins
Organisms: Haemophilus influenzae
Papers: 1

Paper Information1

Evolution of mutations in the ftsI gene leading to amino acid substitutions in PBP3 in Haemophilus influenzae strains under the selective pressure of ampicillin and cefuroxime.

PMID 38954914 · 2024

ftsI

Mutation Information

ftsI: p.K527N

Protein Change: K527N
Organisms: Haemophilus influenzae
Confers Resistance To: cephalosporins
Effect on Function: penicillin-binding protein PBP3 FtsI
Source Database: Reference Gene Catalog

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