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Browse Mutations envZI412L

GeneenvZ

Protein ChangeI412L

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: two-component system sensor histidine kinase EnvZ
Resistance To: ceftazidime avibactam
Organisms: Klebsiella pneumoniae
Papers: 1

Paper Information1

1

Selection of mutants with resistance or diminished susceptibility to ceftazidime/avibactam from ESBL- and AmpC-producing Enterobacteriaceae.

PMID 30247546 · 2018

envZ

Mutation Information

Protein Change: I412L
Organisms: Klebsiella pneumoniae
Confers Resistance To: ceftazidime avibactam
Effect on Function: two-component system sensor histidine kinase EnvZ
Source Database: Reference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research