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Browse Mutations parCE91A

GeneparC

Protein ChangeE91A

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: DNA topoisomerase IV subunit A ParC
Resistance To: fluoroquinolones, quinolones
Organisms: Neisseria gonorrhoeae
Papers: 2

Paper Information2

1

Whole-Genome Sequencing of Russian Neisseria Gonorrhoeae Isolates Related to ST 1407 Genogroup.

PMID 30397529 · 2018

Mutation Information

Protein Change: E91A
Organisms: Neisseria gonorrhoeae
Confers Resistance To: fluoroquinolones
Validation Method: whole-genome sequencing and analysis
Source Database: Reslit

2

Whole-Genome Sequencing to Predict Antimicrobial Susceptibility Profiles in Neisseria gonorrhoeae.

PMID 36735316 · 2023

parC

Mutation Information

Protein Change: E91A
Organisms: Neisseria gonorrhoeae
Confers Resistance To: quinolones
Effect on Function: DNA topoisomerase IV subunit A ParC
Source Database: Reference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research