ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeL434V

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: penicillin-binding protein PBP3 FtsI
Resistance To: carbapenems
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

Penicillin-binding protein 3 is a common adaptive target among Pseudomonas aeruginosa isolates from adult cystic fibrosis patients treated with β-lactams.

PMID 30664925 · 2019

ftsI

Mutation Information

ftsI: p.L434V

Protein Change: L434V
Organisms: Pseudomonas aeruginosa
Confers Resistance To: carbapenems
Effect on Function: penicillin-binding protein PBP3 FtsI
Source Database: Reference Gene Catalog

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