ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneftsI

Protein ChangeV523M

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: penicillin-binding protein PBP3 FtsI
Resistance To: ceftazidime, carbapenems
Organisms: Pseudomonas aeruginosa
Papers: 2

Paper Information2

Evolution of Habitat-Dependent Antibiotic Resistance in Pseudomonas aeruginosa.

PMID 35766499 · 2022

Mutation Information

ftsI: p.V523M

Protein Change: V523M
Organisms: Pseudomonas aeruginosa
Confers Resistance To: ceftazidime
Validation Method: Sanger sequencing
Source Database: Reslit

Hypermutator Pseudomonas aeruginosa Exploits Multiple Genetic Pathways To Develop Multidrug Resistance during Long-Term Infections in the Airways of Cystic Fibrosis Patients.

PMID 32071060 · 2020

ftsI

Mutation Information

ftsI: p.V523M

Protein Change: V523M
Organisms: Pseudomonas aeruginosa
Confers Resistance To: carbapenems
Effect on Function: penicillin-binding protein PBP3 FtsI
Source Database: Reference Gene Catalog

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