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Browse Mutations gyrBE468H

GenegyrB

Protein ChangeE468H

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB
Resistance To: quinolones
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Quantitative contributions of target alteration and decreased drug accumulation to Pseudomonas aeruginosa fluoroquinolone resistance.

PMID 23274661 · 2013

gyrB

Mutation Information

Protein Change: E468H
Organisms: Pseudomonas aeruginosa
Confers Resistance To: quinolones
Effect on Function: DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB
Source Database: Reference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research