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Browse Mutations pmrBS257D

GenepmrB

Protein ChangeS257D

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: two-component system sensor histidine kinase PmrB
Resistance To: colistin
Organisms: Pseudomonas aeruginosa
Papers: 2

Paper Information2

1

PmrB mutations promote polymyxin resistance of Pseudomonas aeruginosa isolated from colistin-treated cystic fibrosis patients.

PMID 22106224 · 2012

pmrB

Mutation Information

Protein Change: S257D
Organisms: Pseudomonas aeruginosa
Confers Resistance To: colistin
Effect on Function: two-component system sensor histidine kinase PmrB
Source Database: Reference Gene Catalog

2

Are there "innocent" amniotic bands?

PMID 3518455 · 1986

pmrB

Mutation Information

Protein Change: S257D
Organisms: Pseudomonas aeruginosa
Confers Resistance To: colistin
Effect on Function: two-component system sensor histidine kinase PmrB
Source Database: Reference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research