ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeP585S

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: DNA topoisomerase IV subunit B ParE
Resistance To: quinolones
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

Topoisomerase mutations that are associated with high-level resistance to earlier fluoroquinolones in Staphylococcus aureus have less effect on the antibacterial activity of besifloxacin.

PMID 21996946 · 2011

parE

Mutation Information

parE: p.P585S

Protein Change: P585S
Organisms: Staphylococcus aureus
Confers Resistance To: quinolones
Effect on Function: DNA topoisomerase IV subunit B ParE
Source Database: Reference Gene Catalog

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