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Browse Mutations rpoBS492L

GenerpoB

Protein ChangeS492L

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: rifampicin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Compensatory evolution in rifampin-resistant Escherichia coli.

PMID 11102350 · 2000

The study focuses on compensatory evolution in rifampin-resistant E. coli, highlighting mutations in the rpoB gene.

Mutation Information

Protein Change: S492L
Organisms: Escherichia coli
Confers Resistance To: rifampicin
Validation Method: experimental validation through fitness measurements and sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research