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Browse Mutations ampDY127H

GeneampD

Anhydro-N-acetylmuramyl tripeptide amidase

Protein ChangeY127H

Nucleotide ChangeT381C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ceftazidime avibactam|imipenem relebactam
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Pseudomonas aeruginosa chronic infections in patients with bronchiectasis: a silent reservoir of carbapenemase-producing epidemic high-risk clones.

PMID 40201539 · 2025

associated with overexpression of AmpC

Mutation Information

ampD: p.Y127H / c.T381C

Protein Change: Y127H
Nucleotide Change: T381C
Organisms: Pseudomonas aeruginosa
Confers Resistance To: ceftazidime avibactam|imipenem relebactam
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research