ResLit - Antimicrobial Resistance Gene & Mutation Database

Outer Membrane Porin (Opr);resistance-nodulation-cell division (RND) antibiotic efflux pump

Protein ChangeS170N

Validation StatusCandidate

Databases

Reslit

Overview

Paper Information2

Characterization of Antimicrobial Resistance Mechanisms in Clinical Isolates of Pseudomonas aeruginosa from a Cystic Fibrosis Patient

Differences in antimicrobial resistance between exoU and exoS isolates of Pseudomonas aeruginosa.

Mutations in parR were associated with aminoglycoside resistance.

Mutations in ParR correlate with aminoglycoside resistance

Protein Change: S170N
Organisms: Pseudomonas aeruginosa
Confers Resistance To: gentamicin|tobramycin
Validation Method: whole genome sequencing and antibiotic susceptibility testing; association with resistance
Source Database: Reslit

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