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Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations rpoBH447Y

GenerpoB

Protein ChangeH447Y

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: rifamycins
Papers: 1

Paper Information1

1

Next-generation rifamycins for the treatment of mycobacterial infections.

PMID 40310456 · 2025

Mutation Information

Protein Change: H447Y
Confers Resistance To: rifamycins
Validation Method: selection of spontaneous resistant mutants and targeted sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research