Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
Rv0678 Membrane-bound transcriptional regulator | A84V | - | - | bedaquiline|clofazimineclofazimine | Reslit | Supported | |
Rv0678 transcriptional repressor of efflux genes | A86V | - | - | Mycobacterium tuberculosis | bedaquiline | Reslit | Candidate |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | A88V | - | - | - | bedaquiline|clofazimine | Reslit | Candidate |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | A92V | - | - | - | bedaquiline|clofazimine | Reslit | Candidate |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | A97V | - | - | - | bedaquiline|clofazimine | Reslit | Candidate |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | A98V | - | - | - | bedaquiline|clofazimine | Reslit | Candidate |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | A99V | - | - | - | bedaquiline|clofazimine | Reslit | Candidate |
| C46R | - | single resistance variant | Mycobacterium tuberculosis | bedaquilineclofazimine | Card Database | Established | |
Rv0678 transcription repressor for efflux pump MmpL5 | C46Y | - | - | - | clofazimine | Reslit | Candidate |
| D88A | - | - | - | bedaquilinebedaquiline|clofazimine | Reslit | Candidate |
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