Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	G442W	G1326T	-	Staphylococcus aureus, Mycobacterium tuberculosis	rifampicin	ResFinder DatabaseReslit	Confirmed
rpoB DNA-directed RNA polymerase subunit beta	G450D	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	G469C	-	-	Geobacillus kaustophilus, Bacillus subtilis	rifampicin	Reslit	Candidate
rpoB β subunit of RNA polymerase	G479D	-	-	Listeria monocytogenes	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	G482D	-	upregulation of a previously uncharacterized operon (prdRAB) that leads to cell membrane remodelling and cross-resistance to daptomycin through reduced binding of the antibiotic, DNA-directed RNA polymerase subunit beta RpoB	Enterococcus faecium	rifampicindaptomycindaptomycin\|rifaximin	Reference Gene CatalogReslit	Confirmed
rpoB RNA polymerase beta subunit	G489V	-	-	Staphylococcus aureus	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	G502K	-	-	Riemerella anatipestifer	rifampicin	Reslit	Candidate
rpoB β subunit of RNA polymerase	G507D	-	-	Mycobacterium smegmatis, Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB β subunit of RNA polymerase	G507S	-	-	Mycobacterium smegmatis, Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB	G510R	-	DNA-directed RNA polymerase subunit beta RpoB	Clostridioides difficile	rifaximin	Reference Gene Catalog	Established