Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	H553N	C1657A	DNA-directed RNA polymerase subunit beta RpoB	Neisseria gonorrhoeae, Neisseria meningitidis	rifampicinceftriaxone	Reference Gene CatalogReslit	Confirmed
rpoB	H553R	-	DNA-directed RNA polymerase subunit beta RpoB	Neisseria meningitidis	rifampicin	Reference Gene Catalog	Established
rpoB RNA polymerase beta subunit	H553Y	-	The H553Y mutation in rpoB confers rifampin resistance., DNA-directed RNA polymerase subunit beta RpoB	Neisseria meningitidis	penicillinrifampicin	Reference Gene CatalogReslit	Confirmed
rpoB	H835R	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB RNA polymerase beta subunit	H87G	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	H929P	-	dysregulation of RNAP transcription activity	Staphylococcus aureus	oxacillin\|cefoxitin\|imipenem	Reslit	Candidate
rpoB	H929Q	-	DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	beta lactams	Reference Gene Catalog	Established
rpoB RNA-polymerase beta-subunit	I1106T	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card DatabaseReslit	Confirmed
rpoB DNA-directed RNA polymerase beta subunit	I1491S	-	-	Mycobacterium bovis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	I170V	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate