Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB	L452M	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB RNA-polymerase beta-subunit	L452P	CTG->CCC T1354C CTT->CCC C1355T	single resistance variant	Mycobacterium tuberculosis, Mycobacterium smegmatis, Mycobacterium bovis	rifampicinrifampicin\|rifabutin	Card DatabaseResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	L452Q	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB	L452R	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB	L452V	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB	L452Var	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB RNA polymerase beta subunit	L455P	-	-	Mycobacterium leprae	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	L456I	-	-	-	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	L457P	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card DatabaseResFinder DatabaseReslit	Confirmed
rpoB	L457R	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established