Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
rpoB RNA polymerase beta subunit | L494P | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
rpoB RNA polymerase beta subunit | L511P | - | Mycobacterium tuberculosis, Mycobacterium smegmatis | rifampicinrifabutin | Reslit | Supported | |
rpoB RNA polymerase beta subunit | L511Q | - | DNA-directed RNA polymerase subunit beta RpoB | Mycobacterium tuberculosis, Shigella sonnei | rifampicin | Reference Gene CatalogReslit | Confirmed |
rpoB RNA polymerase beta subunit | L511R | - | Mycobacterium tuberculosis, Escherichia coli | rifampicin | Reslit | Supported | |
rpoB RNA polymerase B subunit | L511V | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
rpoB RNA polymerase subunit | L516P | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
| L516V | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate | |
rpoB β subunit of RNA polymerase | L521M | - | - | Mycobacterium smegmatis | rifampicin | Reslit | Candidate |
rpoB RNA polymerase beta subunit | L521P | - | - | Mycobacterium bovis | rifampicin | Reslit | Candidate |
rpoB RNA polymerase beta subunit | L521Y | - | enhances rifampicin binding | Escherichia coli | rifampicin | Reslit | Candidate |
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