Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	L531L	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	L531P	T1593C	-	Mycobacterium tuberculosis	rifampicin	Reslit	Supported
rpoB RNA polymerase beta subunit	L531S	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	L531V	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase subunit beta	L533A	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	L533E	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	L533P	CTG-CCG CTT->CCT T1600C	did not significantly change the intermolecular interaction between RpoB and RIF, Target modification, single resistance variant, DNA-directed RNA polymerase subunit beta RpoB	Mycobacterium tuberculosis, Mycobacterium smegmatis, Escherichia coli, Shigella sonnei	rifampicinrifabutinrifamycins	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	L533Q	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	L533R	CTT->CGT	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase β-chain	L538I	-	-	Pseudomonas aeruginosa	rifampicin	Reslit	Candidate