Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
Rv0678 transcriptional repressor of the MmpS5-MmpL5 drug export pump | F100Y | - | - | - | bedaquiline | Reslit | Candidate |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | F79C | - | - | - | bedaquiline|clofazimine | Reslit | Candidate |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | F79V | - | - | - | bedaquiline|clofazimine | Reslit | Candidate |
Rv0678 Membrane-bound transcriptional regulator | F93L | - | - | bedaquiline|clofazimine | Reslit | Candidate | |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | G103R | - | - | - | bedaquiline|clofazimine | Reslit | Candidate |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | G121E | - | - | - | bedaquiline|clofazimine | Reslit | Candidate |
Rv0678 repressor of the MmpS5-MmpL5 efflux pump | G121R | single resistance variant | Mycobacterium tuberculosis | bedaquiline|clofaziminebedaquilineclofazimine | Card DatabaseReslit | Confirmed | |
| G123D | - | - | - | bedaquiline | Reslit | Candidate | |
Rv0678 putative membrane protein | G25C | - | - | Mycobacterium tuberculosis | bedaquiline | Reslit | Candidate |
Rv0678 repressor protein that regulates mmpS5/mmpL5 efflux pump gene expression | G25D | - | - | - | bedaquiline|clofazimine | Reslit | Candidate |
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