Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
walK histidine kinase of TCS WalRK	N283E	-	-	L. monocytogenes	penicillin	Reslit	Candidate
walK two-component regulatory system	N70K	-	-	Staphylococcus haemolyticus	vancomycin	Reslit	Candidate
walK serine/threonine protein kinase	R123K	-	-	Staphylococcus aureus	daptomycin	Reslit	Candidate
walK	R263C	-	single resistance variant, cell wall metabolism sensor histidine kinase WalK	Staphylococcus aureus	daptomycin	Card DatabaseReference Gene Catalog	Confirmed
walK two-component regulatory system	R280Q	-	-	Staphylococcus haemolyticus	vancomycin	Reslit	Candidate
walK serine/threonine protein kinase	R282C	-	-	Staphylococcus aureus	vancomycin	Reslit	Candidate
walK histidine kinase	R86C	-	-	-	methicillin	Reslit	Candidate
walK two-component system sensor kinase	S221P	G662C	reduced autophosphorylation status of WalK, thereby decreasing the phosphorylation and transcriptional activity of WalR, enhanced vancomycin resistance, single resistance variant, cell wall metabolism sensor histidine kinase WalK	Staphylococcus aureus	vancomycindaptomycin	Card DatabaseReference Gene CatalogReslit	Confirmed
walK serine/threonine protein kinase	S437F	-	-	Staphylococcus aureus	vancomycin	Reslit	Candidate
walK serine/threonine protein kinase	S9P	-	-	Staphylococcus aureus	vancomycin	Reslit	Candidate