Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
cls	K59T	-	single resistance variant, cardiolipin synthase Cls	Enterococcus faecium	daptomycin	Card DatabaseReference Gene Catalog	Confirmed
cls cardiolipin synthetase	K60T	-	-	-	daptomycin	Reslit	Candidate
cls cardiolipin synthetase	L38V	CTG->GTC	-	-	daptomycin	Reslit	Candidate
cls	L52F	-	single resistance variant, cardiolipin synthase Cls	Staphylococcus aureus	daptomycin	Card DatabaseReference Gene Catalog	Confirmed
cls cardiolipin synthase	N13I	A38T	single resistance variant, cardiolipin synthase Cls	Enterococcus faecium, Enterococcus faecalis	daptomycin	Card DatabaseReference Gene CatalogReslit	Confirmed
cls cardiolipin synthase	N13S	A39G	cardiolipin synthase Cls	Enterococcus faecium	daptomycin	Reference Gene CatalogReslit	Confirmed
cls cardiolipin synthase	N13T	A38C	single resistance variant, cardiolipin synthase Cls	Enterococcus faecium	daptomycin	Card DatabaseReference Gene CatalogReslit	Confirmed
cls	NFQ77del	-	cardiolipin synthase Cls	Enterococcus faecalis	daptomycin	Reference Gene Catalog	Established
cls cardiolipin synthase	R211Q	C631T	increased cardiolipin synthesis activity, cardiolipin synthase Cls	Enterococcus faecium	daptomycin	Reference Gene CatalogReslit	Confirmed
cls cardiolipin synthetase	R218Q	C653A	single resistance variant, cardiolipin synthase Cls	Enterococcus faecalis, Enterococcus faecium	daptomycin	Card DatabaseReference Gene CatalogReslit	Confirmed