Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | S65G | - | - | - | bedaquiline|clofazimine | Reslit | Candidate |
Rv0678 transcription repressor for efflux pump MmpL5 | S68G | - | - | Mycobacterium tuberculosis | clofaziminebedaquiline|clofazimine | ResFinder DatabaseReslit | Confirmed |
Rv0678 mmpR5 repressor protein | T33A | - | substantially affects the DNA binding affinity of the MmpR transcriptional repressor, single resistance variant | Mycobacterium tuberculosis | bedaquiline|clofaziminebedaquiline | Card DatabaseReslit | Confirmed |
Rv0678 transcription repressor for efflux pump MmpL5 | T33N | - | - | - | clofazimine | Reslit | Candidate |
Rv0678 MmpR transcriptional repressor | T91P | - | - | Mycobacterium tuberculosis | bedaquiline | Reslit | Candidate |
Rv0678 hypothetical protein | V152A | - | - | Mycobacterium tuberculosis | bedaquiline | Reslit | Candidate |
Rv0678 repressor protein that regulates mmpS5/mmpL5 efflux pump gene expression | V1A | - | - | - | bedaquiline|clofazimine | Reslit | Candidate |
Rv0678 transcriptional repressor regulating the efflux pump MmpS5-MmpL5 | V1V | - | - | bedaquiline|clofazimine | Reslit | Candidate | |
Rv0678 transcription repressor for efflux pump MmpL5 | V20F | - | - | - | clofazimine | Reslit | Candidate |
Rv0678 Membrane-bound transcriptional regulator | W42R | - | - | bedaquiline|clofazimine | Reslit | Candidate |
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