Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
Rv0678 transcriptional repressor | R94Q | - | - | Mycobacterium tuberculosis | bedaquiline|clofazimine | ResFinder DatabaseReslit | Confirmed |
Rv0678 hypothetical protein | R96Q | - | - | Mycobacterium tuberculosis | clofazimine | Reslit | Candidate |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | S151P | - | - | - | bedaquiline|clofazimine | Reslit | Candidate |
Rv0678 Membrane-bound transcriptional regulator | S53L | - | - | bedaquiline|clofazimineclofazimine | Reslit | Candidate | |
Rv0678 unknown | S53P | - | - | Mycobacterium tuberculosis | bedaquiline|clofaziminebedaquiline | Reslit | Candidate |
| S53Ter | - | nonsense mutation | Mycobacterium tuberculosis | bedaquiline | Card Database | Established | |
| S63G | - | - | Mycobacterium tuberculosis | bedaquilinebedaquiline|clofazimine | Reslit | Supported | |
Rv0678 transcription repressor for efflux pump MmpL5 | S63N | - | - | - | clofazimine | Reslit | Candidate |
| S63R | - | - | Mycobacterium tuberculosis | bedaquilinebedaquiline|clofazimine | ResFinder DatabaseReslit | Confirmed | |
Rv0678 transcriptional repressor of the MmpS5-MmpL5 efflux system | S64G | - | - | - | bedaquiline|clofazimine | Reslit | Candidate |
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