Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
fabI enoyl-[ACP] reductase | L12P | - | - | Enterococcus faecalis | triclosan | Reslit | Candidate |
fabI enoyl-acyl carrier protein reductase | M159T | - | single resistance variant, enoyl-[acyl-carrier-protein] reductase FabI | Escherichia coli | triclosanmultiple antibiotics | Card DatabaseReference Gene CatalogReslit | Confirmed |
fabI enoyl-acyl carrier protein reductase | N220I | - | Staphylococcus aureus | triclosan | Reslit | Candidate | |
fabI enoyl-acyl carrier protein reductase | S166N | - | Staphylococcus aureus | triclosan | Reslit | Candidate | |
fabI enoyl-acyl carrier protein reductase | S241F | - | - | - | triclosan | Reslit | Candidate |
fabI enoyl-acyl carrier protein reductase | T194S | - | - | Escherichia coli | triclosan | Reslit | Candidate |
fabI enoyl-acyl carrier protein reductase | V241I | - | Staphylococcus aureus | triclosan | Reslit | Candidate | |
fabI enoyl-acyl carrier protein reductase | Y123H | - | Staphylococcus aureus | triclosan | Reslit | Candidate | |
fabI enoyl-acyl carrier protein reductase | Y147H | - | FabI(Y147H) was catalytically defective but retained its sensitivity to AFN-1252 | Staphylococcus aureus | triclosan | Reslit | Candidate |
fabR Transcriptional regulator | A63D | - | - | E. coli, K. pneumoniae | avibactam | Reslit | Candidate |
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