Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ftsI	A419G	-	penicillin-binding protein PBP3 FtsI	Pseudomonas aeruginosa	carbapenems	Reference Gene Catalog	Established
ftsI Penicillin-binding protein 3	A437S	GCA->TCA	penicillin-binding protein PBP3 FtsI	Haemophilus influenzae	ampicillin\|cefotaximeampicillin\|penicillinbeta lactams	Reference Gene CatalogReslit	Confirmed
ftsI	A454V	-	penicillin-binding protein PBP3 FtsI	Pseudomonas aeruginosa	carbapenems	Reference Gene Catalog	Established
ftsI	A498T	-	penicillin-binding protein PBP3 FtsI	Escherichia coli	cephalosporins	Reference Gene Catalog	Established
ftsI Penicillin-binding protein 3	A502S	-	-	-	ampicillin\|cefotaxime	Reslit	Candidate
ftsI Penicillin-binding protein 3	A502T	GCA->ACA	penicillin-binding protein PBP3 FtsI	Haemophilus influenzae	ampicillin\|cefotaximeampicillin\|penicillinampicillin+1 more	Reference Gene CatalogReslit	Confirmed
ftsI penicillin-binding protein 3	A502V	GCA->GTA	-	Haemophilus influenzae	ampicillin\|amoxicillinampicillin\|cefotaximeampicillin\|penicillin+2 more	Reslit	Supported
ftsI penicillin-binding protein	A515V	-	increased binding affinity and sequestration of meropenem, penicillin-binding protein PBP3 FtsI	Acinetobacter baumannii	meropenemcarbapenems\|sulbactam durlobactam	Reference Gene CatalogReslit	Confirmed
ftsI Penicillin-binding protein 3	A530S	GCA->TCA	penicillin-binding protein PBP3 FtsI	Haemophilus influenzae	ampicillin\|cefotaximeampicillin\|penicillinimipenem+2 more	Reference Gene CatalogReslit	Confirmed
ftsI Penicillin-binding protein 3	A539T	-	penicillin-binding protein PBP3 FtsI	Pseudomonas aeruginosa	ceftolozane tazobactamcarbapenems	Reference Gene CatalogReslit	Confirmed