Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ftsI penicillin-binding protein	N117S	-	-	Pseudomonas aeruginosa	ceftazidime avibactam	Reslit	Candidate
ftsI	N337NYRIN	-	penicillin-binding protein PBP3 FtsI	Escherichia coli	aztreonam\|cefiderocol\|cephalosporins	Reference Gene Catalog	Established
ftsI penicillin-binding protein 3	N366Y	-	-	Escherichia coli	aztreonam\|ceftazidime avibactam	Reslit	Candidate
ftsI penicillin-binding protein 3	N422I	-	-	Haemophilus influenzae	cefotaxime	Reslit	Candidate
ftsI	N427L	-	penicillin-binding protein PBP3 FtsI	Pseudomonas aeruginosa	carbapenems	Reference Gene Catalog	Established
ftsI	N427S	-	penicillin-binding protein PBP3 FtsI	Pseudomonas aeruginosa	carbapenems	Reference Gene Catalog	Established
ftsI penicillin-binding protein 3	N526H	-	penicillin-binding protein PBP3 FtsI	Haemophilus influenzae	ampicillin\|amoxicillin clavulanic acidcephalosporins	Reference Gene CatalogReslit	Confirmed
ftsI penicillin-binding protein 3	N526K	AAT->AAA A1576G	penicillin-binding protein PBP3 FtsI	Haemophilus influenzae, Streptococcus pyogenes, Streptococcus pneumoniae	ampicillin\|amoxicillinampicillin\|amoxicillin clavulanic acidampicillin\|cefotaxime+8 more	Reference Gene CatalogReslit	Confirmed
ftsI penicillin-binding protein 3	N526L	-	-	-	imipenem	Reslit	Candidate
ftsI penicillin-binding protein 3	N569S	A1706T	-	Haemophilus influenzae	ampicillin\|amoxicillin clavulanic acidampicillin\|cefotaximeampicillin+2 more	Reslit	Supported