Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ftsI penicillin-binding protein 3	R501C	CGT->TGT	-	Haemophilus influenzae	ampicillin\|penicillin	Reslit	Candidate
ftsI Penicillin-binding protein 3	R501L	-	-	-	ampicillin\|cefotaxime	Reslit	Candidate
ftsI Penicillin-binding protein 3 (PBP3)	R504C	-	penicillin-binding protein PBP3 FtsI	Pseudomonas aeruginosa	ceftazidime\|meropenem\|aztreonamceftazidimemeropenem+4 more	Reference Gene CatalogReslit	Confirmed
ftsI Penicillin-binding protein 3 (PBP3)	R504H	-	-	Pseudomonas aeruginosa	ceftazidime\|meropenem\|aztreonamceftazidimeaztreonam	Reslit	Supported
ftsI	R504L	-	penicillin-binding protein PBP3 FtsI	Pseudomonas aeruginosa	carbapenems	Reference Gene Catalog	Established
ftsI penicillin-binding protein 3	R517H	CGT->CAT C1549T	penicillin-binding protein PBP3 FtsI	Haemophilus influenzae	ampicillin\|amoxicillinampicillin\|cefepimeampicillin\|cefotaxime+7 more	Reference Gene CatalogReslit	Confirmed
ftsI penicillin-binding protein 3	S357N	TCA->AAC	penicillin-binding protein PBP3 FtsI	Haemophilus influenzae, non-typeable Haemophilus	ampicillin\|amoxicillinampicillin\|cefotaximeampicillin\|amoxicillin clavulanic acid+4 more	Reference Gene CatalogReslit	Confirmed
ftsI	S365Y	-	penicillin-binding protein PBP3 FtsI	Escherichia coli	ceftibuten\|ceftibuten avibactam	Reference Gene Catalog	Established
ftsI	S368L	-	penicillin-binding protein PBP3 FtsI	Pseudomonas aeruginosa	carbapenems	Reference Gene Catalog	Established
ftsI penicillin-binding protein 3	S385T	TCA->ACA	penicillin-binding protein PBP3 FtsI	Haemophilus influenzae	ampicillin\|amoxicillinampicillin\|cefotaximeampicillin\|amoxicillin clavulanic acid+6 more	Reference Gene CatalogReslit	Confirmed