Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA DNA gyrase	A118S	-	multiple resistance variants, single resistance variant, DNA gyrase subunit A GyrA	Clostridioides difficile	ciprofloxacinmetronidazolefluoroquinolones+1 more	Card DatabaseReference Gene CatalogReslit	Confirmed
gyrA DNA gyrase subunit A	A118T	-	single resistance variant, DNA gyrase subunit A GyrA	Clostridium difficile, Clostridioides difficile	ciprofloxacin\|moxifloxacinfluoroquinolonesquinolones	Card DatabaseReference Gene CatalogReslit	Confirmed
gyrA DNA gyrase A subunit	A119E	-	Target modification, DNA gyrase subunit A GyrA	Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa, Salmonella enterica	norfloxacinciprofloxacinfluoroquinolones+2 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA	A119S	-	Target modification, DNA gyrase subunit A GyrA	Salmonella enterica	nalidixic acid\|ciprofloxacinquinolones	Reference Gene CatalogResFinder Database	Confirmed
gyrA	A119V	-	Target modification, DNA gyrase subunit A GyrA	Salmonella enterica	nalidixic acidquinolones	Reference Gene CatalogResFinder Database	Confirmed
gyrA DNA gyrase subunit A	A126E	-	-	-	levofloxacin\|moxifloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	A126R	-	-	Mycobacterium tuberculosis	fluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	A128S	-	-	Escherichia coli	nalidixic acid\|ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	A129T	-	-	Helicobacter pylori	levofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	A131G	-	Target modification, DNA gyrase subunit A GyrA	Salmonella enterica	fluoroquinolonesnalidixic acid\|ciprofloxacinquinolones	Reference Gene CatalogResFinder DatabaseReslit	Confirmed