Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA DNA gyrase subunit A	E859V	-	-	-	fluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	E85A	-	-	Streptococcus pneumoniae, Streptococcus agalactiae	moxifloxacin\|levofloxacin\|gemifloxacinlevofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	E85G	-	-	Acinetobacter baumannii, Streptococcus pneumoniae	fluoroquinolonesciprofloxacin\|nalidixic acid	Reslit	Supported
gyrA DNA gyrase subunit A	E85K	G253A G254A GAG->AAA G255A	mutation in DNA gyrase subunit A	Streptococcus pneumoniae, Streptococcus agalactiae, Streptococcus pyogenes, Streptococcus suis	levofloxacinfluoroquinolonesmoxifloxacin\|levofloxacin\|gemifloxacin+5 more	Reslit	Supported
gyrA DNA gyrase subunit A	E85V	-	-	Acinetobacter baumannii	fluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	E86K	-	-	Staphylococcus aureus	ciprofloxacin\|levofloxacin\|moxifloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	E871K	-	-	Staphylococcus pseudintermedius	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	E87G	-	Target modification, DNA gyrase subunit A GyrA	Mycoplasma gallisepticum, Enterococcus faecalis, Enterococcus faecium	danofloxacin\|enrofloxacin\|ofloxacin\|levofloxacin\|gatifloxacin\|norfloxacinnalidixic acid\|ciprofloxacinquinolones	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	E87K	GAG -> AAA GAG->AAA	Target modification, DNA gyrase subunit A GyrA	Streptococcus pneumoniae, Enterococcus faecalis, Enterococcus faecium	ciprofloxacinfluoroquinolonesciprofloxacin\|grepafloxacin\|levofloxacin\|sparfloxacin\|trovafloxacin+2 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA	E87L	-	Target modification, DNA gyrase subunit A GyrA	Enterococcus faecalis, Enterococcus faecium	nalidixic acid\|ciprofloxacinquinolones	Reference Gene CatalogResFinder Database	Confirmed