Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
acrR transporter | W178R | - | - | E. coli | tetracycline | Reslit | Candidate |
acrR transcriptional repressor | W50R | - | - | Klebsiella pneumoniae | tigecycline | Reslit | Candidate |
acrR regulator | W63R | - | - | E. coli | ciprofloxacin | Reslit | Candidate |
| Y114F | - | single resistance variant, transcriptional regulator AcrR | Klebsiella pneumoniae | eravacyclinemultiple antibioticstigecycline | Card DatabaseReference Gene CatalogReslit | Confirmed | |
acrR transcriptional repressor of the AcrAB-TolC efflux pump | Y137H | - | - | Escherichia spp. | ciprofloxacin | Reslit | Candidate |
| Y170* | - | - | - | eravacycline | Reslit | Candidate | |
acrS repressor of the AcrAB pump | D167N | - | - | Escherichia coli | fluoroquinolones | Reslit | Candidate |
acrS efflux pump component | S76R | - | - | Klebsiella pneumoniae | colistin | Reslit | Candidate |
adeA Membrane fusion protein of the RND efflux pump | Q335H | - | Neutral | Acinetobacter baumannii | carbapenems | Reslit | Candidate |
adeB efflux pump component | - | - | Klebsiella pneumoniae | phenicols|tetracycline|fluoroquinolones | Reslit | Candidate |
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