Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
liaR two-component system response regulator	-	1234del	-	Enterococcus faecium	daptomycin	Reslit	Candidate
liaR Cell wall stress response regulator	-	T73C	-	-	daptomycin	Reslit	Candidate
liaR LiaFSR signaling pathway regulator	D191N	-	enhances DNA binding affinity and oligomerization, single resistance variant, response regulator transcription factor LiaR	Enterococcus faecalis	daptomycin	Card DatabaseReference Gene CatalogReslit	Confirmed
liaR transcriptional regulator	E75K	-	response regulator transcription factor LiaR	Enterococcus faecalis, Enterococcus faecium	daptomycin	Reference Gene CatalogReslit	Confirmed
liaR response regulator	S19F	-	response regulator transcription factor LiaR	Enterococcus faecium	daptomycin	Reference Gene CatalogReslit	Confirmed
liaR cell envelope stress response regulator	T120A	-	-	Enterococcus faecalis, Enterococcus faecium	daptomycin	Reslit	Candidate
liaR response regulator	W73C	G221T T218C	constitutive activation, mutated, single resistance variant, response regulator transcription factor LiaR	Enterococcus faecium	daptomycin	Card DatabaseReference Gene CatalogReslit	Confirmed
liaS Cell wall stress response regulator	-	T120A	-	Enterococcus faecium	daptomycin	Reslit	Candidate
liaS	A180T	-	single resistance variant, sensor histidine kinase LiaS	Enterococcus faecalis, Enterococcus faecium	daptomycin	Card DatabaseReference Gene Catalog	Confirmed
liaS	E192G	-	single resistance variant, sensor histidine kinase LiaS	Enterococcus faecium	daptomycin	Card DatabaseReference Gene Catalog	Confirmed