Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
mcr-1 PEA transferase | N108S | - | - | - | polymyxin b|colistin | Reslit | Candidate |
| P198A | - | Escherichia coli | colistin | Reslit | Candidate | ||
| P198Y | - | Escherichia coli | colistin | Reslit | Candidate | ||
mcr-1 mobile colistin resistance protein | S284D | - | - | E. coli | colistin | Reslit | Candidate |
mcr-1 PEA transferase | S464G | - | - | - | polymyxin b|colistin | Reslit | Candidate |
mcr-1 PEA transferase | T247A | - | - | - | polymyxin b|colistin | Reslit | Candidate |
mcr-1 Phosphoethanolamine transferase | T283A | - | - | Escherichia coli, Salmonella enterica | colistin | Reslit | Candidate |
mcr-1 PEA transferase | T285A | - | - | - | polymyxin b|colistin | Reslit | Candidate |
mcr-2 Phosphoethanolamine transferase | E114K | - | The mutation E114K in MCR-2 was shown to partially confer colistin resistance, as evidenced by the presence of a specific peak for PPEA-1(4′)-lipid A in MALDI-TOF MS analysis. | Escherichia coli, Salmonella enterica | colistin | Reslit | Candidate |
mcr-2 Phosphoethanolamine transferase | H393R | - | The mutation H393R in MCR-2 was shown to partially confer colistin resistance, as evidenced by the presence of a specific peak for PPEA-1(4′)-lipid A in MALDI-TOF MS analysis. | Escherichia coli, Salmonella enterica | colistin | Reslit | Candidate |
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