Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
mprF bifunctional enzyme MprF | P314T | - | - | Staphylococcus aureus | daptomycin | Reslit | Candidate |
mprF lysyl-phosphatidylglycerol synthase | R188H | - | - | Pseudomonas aeruginosa | polymyxin b|colistin | Reslit | Candidate |
mprF phosphatidylglycerol lysyltransferase | R301L | - | - | methicillin-resistant Staphylococcus | daptomycin | Reslit | Candidate |
mprF phosphatidylglycerolphosphate synthase | R50H | - | - | - | daptomycin | Reslit | Candidate |
mprF phosphatidylglycerol lysyltransferase | R50L | - | - | methicillin-resistant Staphylococcus | daptomycin | Reslit | Candidate |
mprF Phospholipid flippase | R788L | - | - | daptomycin | Reslit | Candidate | |
mprF phosphatidylglycerol lysyltransferase | R798P | - | - | - | daptomycin | Reslit | Candidate |
mprF Phospholipid flippase | S136L | - | - | daptomycin | Reslit | Candidate | |
mprF membrane-bound phospholipid flippase | S295A | - | - | Staphylococcus aureus | daptomycin | Reslit | Candidate |
mprF lysyl-phosphatidylglycerol synthase | S295L | gain-of-function, gain-in-function, increased enzymatic activity, single resistance variant, bifunctional lysylphosphatidylglycerol flippase/synthetase MprF | Staphylococcus aureus, Staphylococcus epidermidis | daptomycin | Card DatabaseReference Gene CatalogReslit | Confirmed |
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