Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
murAA peptidoglycan synthesis enzyme	A115T	-	-	Enterococcus faecalis	cephalosporins	Reslit	Candidate
murAA peptidoglycan synthesis enzyme	A115V	-	-	Enterococcus faecalis	cephalosporins	Reslit	Candidate
murAA peptidoglycan synthesis enzyme	N188K	-	-	Enterococcus faecalis	cephalosporins	Reslit	Candidate
murD UDP-N-acetylmuramate--L-alanine ligase	T80I	-	-	Mycobacterium tuberculosis	amoxicillin\|meropenem	Reslit	Candidate
murG	P107L	-	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase MurG	Clostridioides difficile	vancomycin	Reference Gene Catalog	Established
murG peptidoglycan glycosyltransferase	P108L	-	single resistance variant	Clostridioides difficile, Clostridium acetobutylicum	vancomycin	Card DatabaseReslit	Confirmed
murG UDP-N-acetylmuramoylalanine--DP-N-acetylmuramidase	R335P	-	-	Mycobacterium tuberculosis	meropenem	Reslit	Candidate
mutH DNA mismatch repair endonuclease	V76G	G227A	disrupts catalysis due to loss of this stabilizing hydrophobic interaction	Klebsiella pneumoniae	ceftazidime avibactam\|meropenem vaborbactam	Reslit	Candidate
mutL DNA mismatch repair protein MutL	-	-	-	Pseudomonas aeruginosa	ceftazidime	Reslit	Candidate
mutL DNA mismatch repair protein	-	G211A	-	Pseudomonas aeruginosa	carbapenems\|fluoroquinolones	Reslit	Candidate