Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
nfsB nitroreductase | R207H | - | - | - | nitrofurantoin | Reslit | Candidate |
nfsB nitrofurantoin reductase | R207L | - | - | - | nitrofurantoin | Reslit | Candidate |
nfsB nitroreductase | S38F | - | - | Escherichia coli | nitrofurantoin | Reslit | Candidate |
nfsB nitrofurantoin reductase | T122C | - | - | - | nitrofurantoin | Reslit | Candidate |
nfsB nitroreductase | W159* | - | - | Escherichia coli | nitrofurantoin | Reslit | Candidate |
nfsB nitroreductase | W46C | - | modification or loss of NfsB is a well-known mechanism of nitrofurantoin resistance in E. coli, leading to inactivated or poor catalytic function, oxygen-insensitive NAD(P)H nitroreductase NfsB | Klebsiella pneumoniae | nitrofurantoin | Reference Gene CatalogReslit | Confirmed |
nfsB nitroreductase | W46R | - | - | Escherichia coli | nitrofurantoin | Reslit | Candidate |
nfsB nitroreductase | W94* | - | - | Escherichia coli | nitrofurantoin | Reslit | Candidate |
| W94Ter | - | oxygen-insensitive NAD(P)H nitroreductase NfsB | Escherichia coli | nitrofurantoin | Reference Gene Catalog | Established | |
nfxB transcriptional repressor of MexCD-OprJ efflux pump | - | - | Pseudomonas aeruginosa | ciprofloxacin | Reslit | Candidate |
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