Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ampC ampcpromotersize53bp	-	C-42G	Enzymatic degradation, ampC/blaEC promoter region	Escherichia coli	ampicillin\|ampicillin clavulanic acid\|amoxicillin\|amoxicillin clavulanic acid\|cefixime\|cefotaxime\|cefoxitin\|ceftazidime\|piperacillincephalosporins	Reference Gene CatalogResFinder Database	Confirmed
ampC beta-lactamase	-	C-42T	increased expression of the chromosomal ampC gene, hyperproduction of AmpC beta-lactamase, Enzymatic degradation, ampC/blaEC promoter region	Escherichia coli, E. fergusonii, Klebsiella pneumoniae	cefotaximecefotaxime\|ceftazidimecefoxitin+3 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
ampC beta-lactamase	-	C-66T	-	Pseudomonas aeruginosa	imipenem\|ampicillin	Reslit	Candidate
ampC chromosomal β-lactamase	-	C-73T	-	Escherichia coli	-	Reslit	Candidate
ampC AmpC beta-lactamase	-	C17T	-	Escherichia coli	ceftazidime\|cefotaxime\|cefepime\|cefoxitin	Reslit	Candidate
ampC extended-spectrum cephalosporinase	-	C315T	-	-	imipenem	Reslit	Candidate
ampC beta-lactamase	-	C58T	hyperproduction of AmpC beta-lactamase	Escherichia coli	cefoxitin\|cefazolin\|ampicillin\|cefotaxime\|ceftazidime\|ceftriaxonebeta lactams	Reslit	Candidate
ampC beta-lactamase	-	G-11A	-	Escherichia coli	-	Reslit	Candidate
ampC	-	G-15GG	ampC/blaEC promoter region	Escherichia coli	cephalosporins	Reference Gene Catalog	Established
ampC AmpC beta-lactamase	-	G-18A	hyperproduction of AmpC beta-lactamase	Escherichia coli, Klebsiella pneumoniae	ceftazidime\|cefotaxime\|cefepime\|cefoxitincephalosporins\|penicillin\|aztreonamcefoxitin+1 more	Reslit	Supported