Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
parC DNA gyrase subunit C	-	recA nucleotide position 1 356 561 to trpB position 1 454 925ins	-	Staphylococcus aureus	vancomycin	Reslit	Candidate
parC topoisomerase IV subunit C	-	TCG->AGG	-	Neisseria gonorrhoeae	ciprofloxacin	Reslit	Candidate
parC topoisomerase IV subunit C	-	TCG->ATC	-	Shigella sonnei	fluoroquinolones	Reslit	Supported
parC DNA topoisomerase IV subunit	-	TCT->TTC	-	Streptococcus pneumoniae	ciprofloxacin\|levofloxacin	Reslit	Candidate
parC DNA topoisomerase IV subunit C	21del	-	-	P. aeruginosa	fluoroquinolones	Reslit	Candidate
parC DNA topoisomerase IV subunit C	27del	-	-	P. aeruginosa	fluoroquinolones	Reslit	Candidate
parC DNA topoisomerase IV subunit A	A103P	-	-	Streptococcus pneumoniae	tosufloxacin\|levofloxacin	Reslit	Candidate
parC topoisomerase IV subunit A	A108T	-	DNA topoisomerase IV subunit A ParC	Escherichia coli	fluoroquinolonesnalidixic acid\|ciprofloxacin\|enrofloxacinquinolones	Reference Gene CatalogReslit	Confirmed
parC DNA topoisomerase IV subunit C	A108V	C325T	DNA topoisomerase IV subunit A ParC	Escherichia coli	nalidixic acid\|ciprofloxacinfluoroquinolonesciprofloxacin+1 more	Reference Gene CatalogReslit	Confirmed
parC	A116E	-	DNA topoisomerase IV subunit A ParC	Staphylococcus aureus	quinolones	Reference Gene Catalog	Established