Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
parC topoisomerase IV subunit C | S1054Y | - | - | - | nalidixic acid | Reslit | Candidate |
parC topoisomerase IV subunit C | S108R | - | - | Staphylococcus agnetis, Staphylococcus saprophyticus | ciprofloxacin | Reslit | Candidate |
parC Topoisomerase IV subunit C | S129P | - | single resistance variant, DNA topoisomerase IV subunit A ParC | Shigella flexneri, Shigella boydii, Escherichia coli | nalidixic acid|norfloxacinciprofloxacinfluoroquinolones+1 more | Card DatabaseReference Gene CatalogReslit | Confirmed |
parC DNA gyrase subunit A | S134R | - | - | Klebsiella pneumoniae | ciprofloxacin | Reslit | Candidate |
| S136A | - | - | Pseudomonas putida | fluoroquinolones | Reslit | Candidate | |
parC DNA topoisomerase IV subunit A | S138T | - | - | Haemophilus parainfluenzae | quinolones | Reslit | Candidate |
parC topoisomerase IV subunit C | S140P | - | - | Streptococcus pyogenes | levofloxacin | Reslit | Candidate |
parC topoisomerase IV subunit | S141H | - | - | Pseudomonas aeruginosa | ciprofloxacin|levofloxacin | Reslit | Candidate |
parC topoisomerase IV subunit | S141T | - | - | Pseudomonas aeruginosa | ciprofloxacin|levofloxacin | Reslit | Candidate |
parC DNA topoisomerase IV subunit C | S151P | - | Escherichia coli | fluoroquinolones | Reslit | Candidate |
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