Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
parC DNA gyrase subunit A	T101I	-	-	Mycoplasma genitalium	fluoroquinolones	Reslit	Candidate
parC	T105P	-	-	Pseudomonas putida	fluoroquinolones	Reslit	Candidate
parC DNA gyrase subunit B	T242A	-	-	Enterococcus faecalis	ciprofloxacin	Reslit	Candidate
parC DNA topoisomerase IV subunit C	T251A	-	-	Klebsiella pneumoniae	fluoroquinolones	Reslit	Candidate
parC DNA topoisomerase IV subunit C	T255S	-	-	-	ciprofloxacin	Reslit	Candidate
parC DNA topoisomerase IV subunit C	T462A	-	-	Yersinia pestis	levofloxacin	Reslit	Candidate
parC DNA topoisomerase IV subunit C	T57S	A171T CCT->AGT A170T	reduced susceptibility to (fluoro)quinolones, Target modification	Salmonella enterica, Salmonella Choleraesuis, Salmonella Derby, Salmonella Typhimurium, Salmonella, Salmonella Kentucky, Salmonella Heidelberg, Salmonella Stanley, Serratia marcescens, Shigella sonnei, Salmonella Isangi, Salmonella Paratyphi, Salmonella Infantis, Salmonella Typhi, non-typhoidal Salmonella	ciprofloxacin\|nalidixic acidciprofloxacinfluoroquinolones+5 more	ResFinder DatabaseReslit	Confirmed
parC DNA gyrase subunit A	T620A	-	-	Salmonella enterica	ciprofloxacin\|nalidixic acid	Reslit	Candidate
parC DNA topoisomerase IV subunit C	T66I	C199T	Target modification, DNA topoisomerase IV subunit A ParC	Escherichia coli, Salmonella enterica	nalidixic acid\|ciprofloxacinquinolones	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
parC topoisomerase IV subunit C	T705A	-	-	Pseudomonas aeruginosa	fluoroquinolones	Reslit	Candidate