Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
parE topoisomerase IV subunit E | E439K | - | - | - | fluoroquinolones | Reslit | Candidate |
| E454G | - | Target modification, DNA topoisomerase IV subunit B ParE | Salmonella enterica | nalidixic acid|ciprofloxacinquinolones | Reference Gene CatalogResFinder Database | Confirmed | |
parE DNA topoisomerase IV | E459D | - | DNA topoisomerase IV subunit B ParE | Pseudomonas aeruginosa | fluoroquinolonesquinolones | Reference Gene CatalogReslit | Confirmed |
parE DNA topoisomerase IV | E459K | - | - | Pseudomonas aeruginosa | fluoroquinolonesciprofloxacin | Reslit | Candidate |
| E459L | - | DNA topoisomerase IV subunit B ParE | Pseudomonas aeruginosa | quinolones | Reference Gene Catalog | Established | |
parE DNA topoisomerase IV subunit B | E459Q | - | - | E. coli | enrofloxacin | Reslit | Candidate |
parE topoisomerase IV subunit E | E459V | - | - | Pseudomonas aeruginosa | fluoroquinolones | Reslit | Candidate |
parE topoisomerase IV subunit B | E460A | - | - | Escherichia coli | nalidixic acid|ciprofloxacin | Reslit | Candidate |
parE DNA topoisomerase IV subunit A | E460D | - | Target modification, DNA topoisomerase IV subunit B ParE | Escherichia coli | ciprofloxacinciprofloxacin|nalidixic acidnalidixic acid|ciprofloxacin+1 more | Reference Gene CatalogResFinder DatabaseReslit | Confirmed |
| E460K | - | DNA topoisomerase IV subunit B ParE | Escherichia coli | quinolones | Reference Gene Catalog | Established |
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