Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| E67Ter | - | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | Pseudomonas aeruginosa | cephalosporins | Reference Gene Catalog | Established | |
ampD regulatory protein involved in AmpC β-lactamase expression | F160* | - | - | cefotaxime|ceftazidime|cefepime | Reslit | Candidate | |
| F191C | - | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | Burkholderia cenocepacia | cephalosporins | Reference Gene Catalog | Established | |
ampD peptidoglycan hydrolase | G100E | - | - | - | meropenem | Reslit | Candidate |
ampD peptidoglycan hydrolase | G116V | - | - | - | meropenem|ceftazidime | Reslit | Candidate |
ampD peptidoglycan hydrolase | G121E | - | - | - | meropenem|ceftazidime | Reslit | Candidate |
| G148A | - | - | Pseudomonas aeruginosa | imipenem|meropenemceftazidime avibactam | Reslit | Candidate | |
ampD peptidoglycan hydrolase | G169C | - | - | - | fluoroquinolones | Reslit | Candidate |
ampD N-acetyl-anhydromuramyl-L-alanine-amidase | H157Y | - | increased basal ampC expression, 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | Pseudomonas aeruginosa | ceftolozane tazobactamimipenemceftazidime+1 more | Reference Gene CatalogReslit | Confirmed |
| H36R | - | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | Pseudomonas aeruginosa | cephalosporins | Reference Gene Catalog | Established |
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