Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp2x penicillin-binding protein 2x	E552K	-	-	-	penicillin\|cefotaxime	Reslit	Candidate
pbp2x penicillin-binding protein 2X	F395L	-	reduced penicillin susceptibility, substitutions in PBP2X are associated with penicillin non-susceptibility	Streptococcus agalactiae	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2X	G398A	-	-	Streptococcus agalactiae	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein	G422D	-	reduced amount of PBP2x	Streptococcus pneumoniae	cefotaxime	Reslit	Candidate
pbp2x penicillin-binding protein 2x	H394L	-	-	Streptococcus pneumoniae	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2X	H438Y	-	substitutions in PBP2X are associated with penicillin non-susceptibility	Streptococcus agalactiae	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2x	I343V	-	-	Streptococcus agalactiae	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2X	I366M	-	-	Streptococcus pneumoniae	cefotaxime	Reslit	Candidate
pbp2x penicillin-binding protein 2x	I371T	-	decreased the affinity of the protein for a β-lactam, single resistance variant	Streptococcus pneumoniae, Streptococcus mitis	penicillin\|cefotaximeamoxicillin	Card DatabaseReslit	Confirmed
pbp2x penicillin-binding protein 2X	I377V	-	substitutions in PBP2X are associated with penicillin non-susceptibility	Streptococcus agalactiae	penicillin	Reslit	Candidate