Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp2x penicillin-binding protein 2x	L364F	-	decreased the affinity of the protein for a β-lactam	Streptococcus pneumoniae, Streptococcus mitis	penicillin\|cefotaxime	Reslit	Candidate
pbp2x penicillin-binding protein 2x	L382I	-	-	Enterococcus cecorum	amoxicillin\|trimethoprim sulfamethoxazoleampicillin\|ceftiofur	Reslit	Candidate
pbp2x penicillin-binding protein	L403F	-	reduced amount of PBP2x	Streptococcus pneumoniae	cefotaxime	Reslit	Candidate
pbp2x penicillin-binding protein 2x	L510T	-	-	Streptococcus pneumoniae, Streptococcus mitis	penicillin\|cefotaxime	Reslit	Candidate
pbp2x penicillin-binding protein 2x	L546V	-	single resistance variant	Streptococcus pneumoniae	penicillinamoxicillin	Card DatabaseReslit	Confirmed
pbp2x penicillin-binding protein	L547V	-	-	Streptococcus mitis/oralis	meropenem	Reslit	Candidate
pbp2x penicillin-binding protein 2X	M339F	ATG->TTT	single resistance variant	Streptococcus pneumoniae	cefotaximepenicillin\|cefotaximepenicillin\|oxacillin+1 more	Card DatabaseReslit	Confirmed
pbp2x penicillin-binding protein 2x	M339L	-	-	-	penicillin\|oxacillin	Reslit	Candidate
pbp2x penicillin-binding protein 2x	M341I	-	-	Streptococcus suis	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2X	M342I	-	-	-	beta lactams	Reslit	Candidate