Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp2x penicillin-binding protein 2X	V405A	-	substitutions in PBP2X are associated with penicillin non-susceptibility	Streptococcus agalactiae	penicillin\|clarithromycin\|levofloxacinpenicillin	Reslit	Supported
pbp2x penicillin-binding protein 2X	V510I	-	substitutions in PBP2X are associated with penicillin non-susceptibility	Streptococcus agalactiae	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2x	V518I	-	-	Streptococcus pneumoniae	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein	V547M	-	-	Streptococcus suis	ceftiofur	Reslit	Candidate
pbp2x penicillin-binding protein 2x	W377S	-	-	Enterococcus cecorum	amoxicillin\|trimethoprim sulfamethoxazoleampicillin\|ceftiofur	Reslit	Candidate
pbp2x penicillin-binding protein 2x	Y331H	-	-	Streptococcus agalactiae	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein	Y382K	-	-	Streptococcus suis	ceftiofur	Reslit	Candidate
pbp2x penicillin-binding protein	Y525F	-	-	Streptococcus suis	ceftiofur	Reslit	Candidate
pbp2x penicillin-binding protein 2x	Y595F	-	decreased the affinity of the protein for a β-lactam	Streptococcus pneumoniae, Streptococcus mitis	penicillin\|cefotaxime	Reslit	Candidate
pbp3 penicillin-binding protein 3	-	A377T	-	Haemophilus influenzae	ampicillin\|amoxicillin clavulanic acid\|cefotiam\|cefdinir	Reslit	Candidate