Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp3 penicillin-binding protein 3	-	A526G	-	Haemophilus influenzae	ampicillin\|amoxicillin clavulanic acid\|cefotiam\|cefdinir	Reslit	Candidate
pbp3 penicillin-binding protein 3	-	C517A	-	Haemophilus influenzae	ampicillin\|amoxicillin clavulanic acid\|cefotiam\|cefdinir	Reslit	Candidate
pbp3 penicillin-binding protein 3	-	T385C	-	Haemophilus influenzae	ampicillin\|amoxicillin clavulanic acid\|cefotiam\|cefdinir	Reslit	Candidate
pbp3 penicillin-binding protein 3	-	T389C	-	Haemophilus influenzae	ampicillin\|amoxicillin clavulanic acid\|cefotiam\|cefdinir	Reslit	Candidate
pbp3 penicillin-binding protein	1del	-	-	-	carbapenems	Reslit	Candidate
pbp3 penicillin-binding protein	A233T	GCT->ACT	-	Escherichia coli	ceftazidime	Reslit	Candidate
pbp3 penicillin-binding protein	A353S	-	-	-	vancomycin	Reslit	Candidate
pbp3 penicillin-binding protein	A413V	-	altered the structural loop adjacent to the active site, potentially diminishing the binding affinity of aztreonam	Klebsiella pneumoniae	ceftazidime\|aztreonam	Reslit	Candidate
pbp3	A499V	-	single resistance variant	Helicobacter pylori	amoxicillin	Card Database	Established
pbp3 penicillin-binding protein 3	A50S	-	single resistance variant	Helicobacter pylori	amoxicillin	Card DatabaseReslit	Confirmed