Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp3 penicillin-binding protein 3	V527I	-	-	Helicobacter pylori	amoxicillin	Reslit	Candidate
pbp3	V562L	-	single resistance variant	Haemophilus influenzae	beta lactams	Card Database	Established
pbp3 penicillin-binding protein 3	V613A	-	-	Staphylococcus aureus	oxacillin	Reslit	Candidate
pbp3 penicillin-binding protein 3	Y721S	G2162C	-	Clostridium difficile	carbapenemsimipenem	Reslit	Candidate
pbp4	-	T-266A	D-alanyl-D-alanine carboxypeptidase PBP4 promoter region	Staphylococcus aureus	cephalosporins	Reference Gene Catalog	Established
pbp4 penicillin-binding protein 4	A409T	-	-	Staphylococcus aureus	vancomycin	Reslit	Candidate
pbp4 penicillin-binding protein 4	D98E	-	-	Staphylococcus aureus	vancomycin	Reslit	Candidate
pbp4 penicillin binding protein 4	E183A	-	Target protection, D-alanyl-D-alanine carboxypeptidase PBP4	Staphylococcus aureus	ceftaroline\|ceftobiproleceftobiprole\|nafcillinnafcillin\|oxacillin+2 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
pbp4 penicillin-binding protein 4	E218K	-	increased survival in the presence of the β-lactams nafcillin and cefoxitin, D-alanyl-D-alanine carboxypeptidase PBP4	Staphylococcus aureus	nafcillin\|cefoxitincephalosporins	Reference Gene CatalogReslit	Confirmed
pbp4 penicillin-binding protein 4	E297K	-	-	Staphylococcus aureus	oxacillin\|penicillin\|amoxicillin clavulanic acid\|ceftaroline	Reslit	Candidate