Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ampR	-	G-98A	-	Pseudomonas aeruginosa	imipenem\|ampicillin	Reslit	Candidate
ampR transcriptional regulator	*297Y	-	-	Pseudomonas aeruginosa	piperacillin	Reslit	Candidate
ampR transcriptional regulator	D135A	-	activator	Escherichia coli	cephalosporins	Reslit	Candidate
ampR transcriptional regulator	D135G	-	single resistance variant, transcriptional regulator AmpR	Pseudomonas aeruginosa, Enterococcus faecium	ceftolozane\|tazobactambeta lactamsaztreonam\|carbapenems\|cephalosporins+2 more	Card DatabaseReference Gene CatalogReslit	Confirmed
ampR transcriptional regulator	D135N	GAC->AAC	upregulates AmpC expression, single resistance variant, transcriptional regulator AmpR	Pseudomonas aeruginosa	ceftolozane\|tazobactamciprofloxacin\|levofloxacinceftazidime+3 more	Card DatabaseReference Gene CatalogReslit	Confirmed
ampR transcriptional activator	D409Y	-	-	Enterobacter cloacae	cefotaxime	Reslit	Candidate
ampR transcriptional activator	D410A	-	-	Enterobacter cloacae	cefotaxime	Reslit	Candidate
ampR AmpR	E273K	-	-	Enterobacter cloacae	cefoxitin\|cefotaxime\|cefepime\|ertapenem\|imipenem\|meropenem	Reslit	Candidate
ampR LysR-type transcriptional regulator	E274fs	GAG->TGA	-	-	ceftazidime	Reslit	Candidate
ampR transcriptional regulator	G154R	-	constitutive activation of ampC expression, ampC hyperproduction, mutated, transcriptional regulator AmpR	Pseudomonas aeruginosa	penicillin\|cephalosporins\|aztreonamceftazidime\|piperacillin tazobactamceftolozane tazobactam\|ceftazidime avibactam+3 more	Reference Gene CatalogReslit	Confirmed