Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pmrB histidine kinase	A226T	-	associated with stable resistance, two-component system sensor histidine kinase PmrB	Acinetobacter baumannii	colistin	Reference Gene CatalogReslit	Confirmed
pmrB Sensor kinase	A226V	-	-	A. baumannii, Acinetobacter baumannii	colistin	Reslit	Supported
pmrB two-component system sensor kinase	A227V	-	constitutive activation, two-component system sensor histidine kinase PmrB	Acinetobacter baumannii, Klebsiella pneumoniae	colistinpolymyxin bpolymyxin b\|colistin	Reference Gene CatalogReslit	Confirmed
pmrB histidine kinase	A236E	-	-	Acinetobacter baumannii	colistin	Reslit	Candidate
pmrB sensor protein PmrB	A246T	-	-	Klebsiella pneumoniae	colistinpolymyxins	Reslit	Supported
pmrB two-component response regulator	A247T	-	two-component system sensor histidine kinase PmrB	Pseudomonas aeruginosa	polymyxin bcolistin	Reference Gene CatalogReslit	Confirmed
pmrB sensor kinase	A248T	-	gain-of-function, two-component system sensor histidine kinase PmrB	Pseudomonas aeruginosa	colistin	Reference Gene CatalogReslit	Confirmed
pmrB sensor kinase	A248V	-	gain-of-function, two-component system sensor histidine kinase PmrB	Pseudomonas aeruginosa	colistin	Reference Gene CatalogReslit	Confirmed
pmrB two-component regulatory system histidine kinase	A252G	-	-	Klebsiella pneumoniae	colistin	Reslit	Candidate
pmrB two-component system histidine kinase	A256G	-	deleterious	Klebsiella pneumoniae	colistin	Reslit	Candidate