Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pmrB histidine kinase	R231L	-	two-component system sensor histidine kinase PmrB	Acinetobacter baumannii	polymyxin bcolistin	Reference Gene CatalogReslit	Confirmed
pmrB transmembrane sensor kinase of the PmrA/PmrB two-component system	R256G	-	deleterious, mutation in pmrB gene	Klebsiella pneumoniae, Providencia stuartii	colistinpolymyxin bpolymyxins	Reslit	Supported
pmrB sensor kinase	R259H	-	gain-of-function, two-component system sensor histidine kinase PmrB	Pseudomonas aeruginosa	colistin	Reference Gene CatalogReslit	Confirmed
pmrB sensor kinase	R263C	C787T	-	Acinetobacter baumannii, Klebsiella pneumoniae	colistin	Reslit	Supported
pmrB sensor kinase	R263H	G787A G790A	-	Acinetobacter baumannii	colistinpolymyxin b	Reslit	Supported
pmrB two-component system histidine kinase	R263L	-	two-component system sensor histidine kinase PmrB	Acinetobacter baumannii	colistin	Reference Gene CatalogReslit	Confirmed
pmrB histidine kinase	R263P	-	-	Acinetobacter baumannii	polymyxin b	Reslit	Candidate
pmrB two-component system histidine kinase	R263S	-	-	Acinetobacter baumannii	colistin	Reslit	Candidate
pmrB two-component regulatory system histidine kinase	R315P	-	-	Klebsiella pneumoniae	colistin	Reslit	Candidate
pmrB two-component system sensor kinase	R342D	-	-	Klebsiella pneumoniae	colistin	Reslit	Candidate