Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
rpoB RNA polymerase beta subunit | D441F | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
rpoB RNA polymerase beta subunit | D441N | - | - | Mycobacterium tuberculosis, Mycobacterium leprae | rifampicin | Reslit | Candidate |
rpoB RNA polymerase beta subunit | D441V | - | - | Mycobacterium tuberculosis, Mycobacterium leprae | rifampicin | Reslit | Supported |
rpoB RNA polymerase beta subunit | D441Y | - | Mycobacterium tuberculosis, Mycobacterium leprae | rifampicin | Reslit | Supported | |
rpoB RNA polymerase beta subunit | D449N | - | - | Staphylococcus aureus | phenicols|linezolid|retapamulin|quinupristin dalfopristin | Reslit | Candidate |
| D450V | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate | ||
rpoB DNA-directed RNA polymerase beta subunit | D452N | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
rpoB β-subunit of the bacterial RNA polymerase (RNAP) | D461A | - | - | Chlamydia suis | rifamycins | Reslit | Candidate |
rpoB RNA polymerase beta subunit | D461E | - | - | Chlamydia pneumoniae | rifamycinsrifampicin|rifalazil | Reslit | Candidate |
rpoB RNA polymerase subunit | D461N | - | - | Chlamydia trachomatis | rifampicin | Reslit | Candidate |
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